Abstract The microenvironment of immunosuppression and low immunogenicity of tumor cells has led to unsatisfactory therapeutic effects of the currently developed nanoplatforms.Immunogenic cell death, such as pyroptosis and ferroptosis, can efficiently boost antitumor immunity.However, the exploration of nanoplatform for dual function inducers and c
The Effect Of Adding Hydrogenated Coconut Oil And The Time Of Adding Cocoa Powder On The Physical And Organoleptic Chocolate Bar
Chocolate beds and tables bars are one of the processed cocoa products that are much loved by Indonesians.The main ingredient used to manufacture chocolate bars is cocoa butter.However, the relatively high price of cocoa butter causes chocolate bar production costs to be high.Hydrogenated coconut oil as an alternative to reduce the use of cocoa but
Brest Union - causes, consequences, historical destiny
The repeated celebrations of the jubilees of the Union of the Ukrainian Orthodox Church with the Roman Apostolic See encourage us to stop once more and deeper comprehend its genesis, that is, to find out the motives of its creators, historical and other reasons that led to the implementation of this crucial and influential act Xbox Original in the
Intrathyroid Parathyroid AdenomasUncommon Tumours at Unusual Sites: A Cross-sectional Study
Introduction: Ectopic Intrathyroid Parathyroid Adenomas (ITPAs) are rare and Shirts known to pose preoperative and intraoperative diagnostic challenges in localisation, resulting in failure of parathyroid surgery.The common histopathological features of these tumours are not elaborately described in literature.Aim: To describe the clinico-pathologi
Global protein conjugation by ubiquitin-like-modifiers during ischemic stress is regulated by microRNAs and confers robust tolerance to ischemia.
Hibernation torpor provides an excellent model of natural tolerance to ischemia.We have previously shown that massive global SUMOylation occurs during hibernation torpor in ground squirrels.We have also shown that overexpression of Ubc9, SUMO-1, or SUMO-2/3 provides protection against ischemic damage in cell lines and cortical neurons exposed to ox